Postdoc - Cancer Genomics
🔔
  • Check out a recent perspective article on using public genomics data (here)
  • Check out our two recent preprints on bioRxiv and medRxiv

Bio

I graduated from Cairo University with a medical degree. After graduation, I spent a year traveling and volunteering with youth organizations to bring some joy and nature to underserved school kids. In 2016, I joined a lab in Jinju, South Korea, to do research. I studied autophagy and its role in development and disease using high-throughput sequencing data. I developed several open-source R packages and Shiny apps to work with gene expression and regulation data. I have recently joined the cancer genomics team at the Institute of Cancer Research in London to work on the genetics of childhood cancer. I spend most days between the Linux terminal, the R console, and the LaTex editor.

Work Experience

  • Postdoctoral Fellow.  The Institute of Cancer Research, UK (2023 - Present)
  • Senior Researcher. Gyeongsang National University, South Korea (2021 - 2023)

Education

  • PhD. Gyeongsang National University - 2021
  • MS. Gyeongsang National University - 2018
  • MBBCh. Cairo University - 2014
  • Lots of online courses

Awards & Fellowships

  • Fellowship. Center for Human Resource Development in Bio-medicine  (2021 - 2022)
  • Young Scientist Program Award. FAOBMB (2021)
  • Young Scientist Program Award. KSBMB (2020 & 2021)
  • Young Pioneer Research Award. Gyeongsang National University (2018 & 2019)

Interests

  • Cancer genomics
  • Drug discovery and repurposing
  • Regulation of gene expression
  • Autophagy in development and disease

Projects


Task specialization in evolving cancer cells


Studying task specialization and trade-offs in evolving cancer cells.


Perturbing biological networks in cancer cell lines


Studying causal biological networks and their perturbation using existing biological knowledge and data.


Transcriptional regulation of RKIP in cancer


Deciphering the regulatory circuits responsible for RKIP loss in different cancer cell models.


(Archived) Regulation of autophagy in development and disease


Studying the regulation of autophagy in development (adipocyte differentiation) and disease (cancer).


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Publications


Maximizing the utility of public data


Mahmoud Ahmed, Hyun Joon Kim, Deok Ryong Kim


Frontiers in Genetics, vol. 14, Frontiers Media SA, 2023 Mar


Tissue-specific gene expression in obese hyperglycemic mice


Mahmoud Ahmed, Omar Elashkar, Jong Youl Lee, Eun Ae Jeong, Kyung Eun Kim, Gu Seob Roh, Deok Ryong Kim


All Life, vol. 15(1), Taylor & Francis, 2022, pp. 555-561


Disruption of cancer cell functions by task-specific drug perturbations


Mahmoud Ahmed, Deok Ryong Kim


Frontiers in Pharmacology, vol. 13, 2022


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Posts


Jan 5, 2023


Public data for the public good


The human genome project galvanized the scientific community around an ambitious goal. It produced several crucial discoveries, and a new era of research began. For the first time, it became possible to estimate the number of human genes and compile a ...


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Dec 26, 2022


The evolutionary war — how to beat cancer in its own game


Cancer evolves. That much is known and agreed upon. Researchers still, however, debate the detailed picture of how cancer came to be and why it still plages our species is subject to debate. Studying cancer through an evolutionary lens could provide an...


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Aug 4, 2022


Gene expression adaptation in yeast, mice, and humans


Coding vs. non-coding variants Mutations produce novelty. The kind of novel variants on which selection acts. These variants fall within two broad categories depending on location in the genome: protein-coding and regulatory sequences. The former pro...


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Contact


Mahmoud Ahmed


Postdoc



Genetics & Epidemiology


The Institute of Cancer Research


London, UK


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